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    Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd

    Tel: +86-543-2616568

    Fax: +86-543-2605568

    Email: info@cydextrin.com

    Add: Boxing Economic Development Zone, Binzhou, Shandong, China

Sulfobutyl Ether-beta-cyclodextrin Sodium Salt From Binzhou Zhiyuan

Sulfobutyl Ether-beta-cyclodextrin Sodium Salt From Binzhou Zhiyuan

DMF No.: 030167 CAS: 182410-00-0 Standard : USP39 Qaulity : injection grade

DMF No.: 030167

Name: sulfobutyl ether-beta-cyclodextrin sodium salt  

Other name : betadex sulfobutyl ether sodium ; sulfobutyl ether-β-cyclodextrin sodium salt 

CAS: 182410-00-0

Abbreviation: SBEBCD

Molecular formula : C42H70-nO35 (C4H8O3S Na)n 

Molecular weight: 1135+158n

Solubility(in 100cm3 solvent, at 25℃) : water:>50g

                                                              Methanol:<0.5g

                                                             Acetone :<0.5g

Qaulity : injection grade / oral grade

Standard : USP39

Package: 500g/bag , 1kg/bag , 2kg/bag, 10kg/drum , 20kg/drum or customized

Use : medical 

Specification : USP39

ITEMS

SPECIFICATION

RESULTS

Appearance

White to off-white solid, free    from foreign matter

Qualify

           Solution Clarity             

A 30%w/v solution in water is    clear and essentially free from particles of foreign matter

Qualify

Identification (IR)

Consistent with SBECD standard

Qualify

Sodium Identification

Identify test are positive for    Sodium

+

Average Degree of Substitution

6.2-6.9

6.7

SBE 1 Content

≤0.2%

0.05%

SBE 2 Content

≤0.8%

0.15%

Water solution pH

pH of    30%w/v solution in water is 4.0-6.8

5.4

Heavy Metals

≤5ppm

<5ppm

Water

≤10%

4.0%

β-Cyclodextrin Content

≤0.1%

Absence

Sodium Chloride

≤0.2%

0.01%

1,4-butane sultone

≤0.5ppm

0.3ppm

4-Hydroxybutane-1-Sulfonic Acid

≤0.09%

0.01%

Disodium bis-(4-sulfobtyl) ether

≤0.05%

0.05%

Assay

95%-105%

99.5%

Bacterial endotoxins

≤25EU/g

≤20EU/g

Microbiology

Total viable aerobic count (mould plus yeast)

≤100CFU/g

20CFU/g

Escherichia Coli

Absence

Absence

Salmonella species

Absence

Absence

mould plus yeast

≤50CFU/g

Absence

Features and applications:

SBE-β-CD is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.


SBE-β-CD has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.



If you're looking for the high-quality sulfobutyl ether-beta-cyclodextrin sodium salt, our company must be your best choice. We're one of the leading manufacturers and supplier with rich experience and wide expertise. Please be rest assured to buy the products from our factory.

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