Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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    Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd

    Tel: +86-543-2616568

    Fax: +86-543-2605568

    Email: info@cydextrin.com

    Add: Boxing Economic Development Zone, Binzhou, Shandong, China

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New pharmaceutical intermediate HP-BCD

Natural cyclodextrin has low water solubility and slow metabolism, which is unfavorable for use, and often accumulates in organs in the form of insoluble cholesterol complex to produce toxicity. In the actual drug design and production, the structure of cyclodextrin is modified to improve its physical and chemical properties. The new dosage form reduces the toxic side effects of the drug to a certain extent, and improves the solubility, dissolution rate and bioavailability of the drug. Among the three main parent cyclodextrins, beta-cyclodextrin has a low cost, a wide range of inclusions, and moderate molecular weight. It is currently the most widely used cyclodextrin product. Due to its low solubility in water and hemolysis, it limits the use of beta cyclodextrin in many applications. Hydroxypropyl beta-cyclodextrin is an ether derivative of beta-cyclodextrin. The introduction of hydroxypropyl groups opens the hydrogen bond in the beta-cyclodextrin molecule, which greatly improves the water solubility.

Experiments have shown that hydroxypropyl beta-cyclodextrin is highly safe.


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Address: Boxing Economic Development Zone, Binzhou, Shandong, China
Tel: +86-0543-2616568
Fax:+86-543-2605568
E-mail:info@cydextrin.com
Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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