Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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    Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd

    Tel: +86-543-2616568

    Fax: +86-543-2605568

    Email: info@cydextrin.com

    Add: Boxing Economic Development Zone, Binzhou, Shandong, China

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Cyclodextrin can bind glutathione

Glutathione is a natural active peptide composed of glutamic acid, cysteine and glycine. Glutathione usually contains reduced glutathione (GSH) and oxidized glutathione (GSSG) in two forms. Generally, only GSH has bioactivity. However, the sulfhydryl group of GSH is easily oxidized into GSSH in water solution and air, thus losing its physiological activity. It is hoped that the appropriate inclusion agent can be used to encapsulate GSH to ensure that the sulfhydryl group is not oxidized, so as to improve the bioavailability of glutathione.

Studies have confirmed that the Glu residues of GSH can be stabilized by cyclodextrin cavity to form stable complexes. The sulfhydryl group on GSH is encapsulated by the large mouth end of alpha-CD in the composite, thus effectively protecting it from oxidation. The results showed that alpha -CD is a good glutathione entrapped agent.

Cyclodextrin can bind glutathione

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Address: Boxing Economic Development Zone, Binzhou, Shandong, China
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E-mail:info@cydextrin.com
Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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