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    Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd

    Tel: +86-543-2616568

    Fax: +86-543-2605568


    Add: Boxing Economic Development Zone, Binzhou, Shandong, China


DMF No.: 030168 CAS: 128446-35-5; 94035-02-6 Standard : USP41/ EP9.0/ CP2015 Qaulity : Pharmaceutical grade / injection grade / cosmetics grade / industry grade

DMF No.:  030168

Name: hydroxypropyl- beta-cyclodextrin  

Other name : hydroxypropyl betadex ; 2-hydroxypropyl-beta-cyclodextirn ;

             Hydroxypropyl-β-cyclodextrin .

Abbreviation : HPBCD

CAS: 128446-35-5; 94035-02-6

EINECS: 420-920-1

Molecular formula :C42H70-nO35(C3H8O2)n

Molecular weight: 1134.98+58n

Qaulity : Pharma grade /injection grade/ food grade / cosmetics grade / industry grade 

Standard : USP41/ EP9.0/ CP2015

Package: 500g/bag , 2kg/bag,  10kg/drum , 20kg/drum or customized


USP 41 Specification :

AppearanceWhite or almost white, amorphous or crystalline powder. Freely soluble in water and in propylene glycol.
IdentificationIRSame absorption bands as USP Hydroxypropyl Betadex RS
Clarity of SolutionPositive
Molar Substitution0.40~1.50
Propylene Glycol≤2.5%
Any Other Single Impurity≤0.25%
Total Impurities Excluding Betadex and Propylene Glycol≤1.0%
Propylene Oxide≤1ppm
Loss on Drying≤10.0%
Clarity of Solution1.0g/2ml water solution is clear and transparent
Bacterial Endotoxins TestAccording to preparation needs
The total aerobic microbial count≤1000cfu/g
The total combined moulds and yeasts count≤100cfu/g

Storage: Preserve in well-closed containers. Store at room temperature.


Hydroxypropyl-beta-cyclodextrin  is one of the most widely used cyclodextrin derivatives in current scientific researches and industry applications. It mainly used in food, pharmaceutical and cosmetics industries.

1. In pharmaceuticals industry, hydroxypropyl-beta-cyclodextrin  can increase solubility and bioavailability of insoluble drugs, so that the efficacy of drugs can last longer with less ingestion of drugs. It can adjust and control drugs release ratio, decrease side effects of drugs, and enhance stability of drugs. hydroxypropyl-beta-cyclodextrin  can be used for oral medication, injection, mucosal delivery systems (including the nasal mucosa, rectum, cornea, etc.), dermal drug delivery systems, lipophilic drugs targeting delivery, and also used as protective agent and stabilizer of protein.

2. In food and perfume industry, hydroxypropyl-beta-cyclodextrin  can enhance the stability of nutritional constituent and extend active time of effective constituent. It can cover up bad smell and bad taste of nutritional constituent. It also can improve production processes and product quality.

3. In cosmetics industry, hydroxypropyl-beta-cyclodextrin  can reduce stimulate of organic molecular in cosmetic to the skin and mucosa. It can enhance the stability of matter, by preventing oxidation and volatilization of nutrients.

If you're looking for the high-quality hydroxypropyl-beta-cyclodextrin, our company must be your best choice. We're one of the leading manufacturers and supplier with rich experience and wide expertise. Please be rest assured to buy the products from our factory.


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